Mike and Molly Cast and Character Guide (2010)

Mike and Molly Cast: Mike & Molly is an American television sitcom that premiered on CBS on September 20, 2010, and concluded its run on May 16, 2016. Created by Mark Roberts, the show gained popularity for its humor, relatable characters, and the unique premise of exploring a romantic relationship between two plus-sized individuals. Set in Chicago, the series follows the lives of Mike Biggs and Molly Flynn as they navigate the ups and downs of love, family, and career.

Mike and Molly Cast
Mike and Molly Cast
Country of originUnited States
Original languageEnglish
No. of seasons6
No. of episodes127 (list of episodes)
Running time18–22 minutes
ReleaseSeptember 20, 2010 –May 16, 2016
Created byMark Roberts
Star castBilly Gardell
Melissa McCarthy
Reno Wilson
Katy Mixon
Nyambi Nyambi
Rondi Reed
Opening theme“I See Love” by Keb’ Mo’
ComposersDennis C. Brown
Grant Geissman
Executive producersChuck Lorre
Al Higgins
Mark Roberts
Camera setupMulti-camera
Production companiesChuck Lorre Productions
Bonanza Productions
Warner Bros. Television
Cast of Mike and Molly

Mike and Molly Cast

The core cast of “Mike & Molly” features talented actors who brought the characters to life with charm and authenticity:

  • Billy Gardell as Mike Biggs: Gardell portrays a good-natured police officer with a penchant for humor and a heart of gold. His performance adds a genuine and likable quality to the character.
  • Melissa McCarthy as Molly Flynn: McCarthy plays a charming and witty teacher with a passion for life and a love of writing. Her dynamic performance earned her critical acclaim and contributed significantly to the show’s success.
  • Reno Wilson as Officer Carl McMillan: Wilson takes on the role of Mike’s best friend and partner on the police force. His comedic timing and camaraderie with Gardell provide many memorable moments throughout the series.
  • Katy Mixon as Victoria Flynn: Mixon plays Molly’s eccentric and free-spirited sister, bringing a mix of humor and heart to the show.
  • Nyambi Nyambi as Samuel: Nyambi portrays Samuel, a waiter at the local diner where Mike and Carl frequently hang out. His interactions with the main characters add depth and humor to the series.
  • Swoosie Kurtz as Joyce Flynn (127 episodes, 2010-2016)
  • Louis Mustillo as Vince (117 episodes, 2010-2016)
  • Rondi Reed as Peggy (84 episodes, 2010-2016)
  • Cleo King as Grandma (57 episodes, 2010-2016)
  • Suzie Q as Jim (50 episodes, 2010-2016)
  • David Anthony Higgins as Harry (27 episodes, 2011-2016)
  • Holly Robinson Peete as Christina (13 episodes, 2011-2014)
  • Casey Washington as Ramirez / Officer Ramirez / Robber #2 (8 episodes, 2014-2016)
  • Eric Womack as Detective (1 episode, 2014-2016)
  • Gerald McRaney as Captain Patrick Murphy (6 episodes, 2012-2013)
  • Reginald VelJohnson as Brother Heywood (6 episodes, 2010-2013)
  • Brendan Patrick Connor as George / Group Leader (5 episodes, 2010-2015)
  • Cheryl Hawker as Lynette (5 episodes, 2011-2015)
  • Eric Allan Kramer as Officer Seely (4 episodes, 2015-2016)
  • Justin Lawrence as Mark (3 episodes, 2013)
  • Marianne Muellerleile as Connie (4 episodes, 2011-2015)
  • Lamont Thompson as Andre (4 episodes, 2010-2013)


The central premise revolves around the romantic relationship between Mike and Molly, two individuals struggling with weight issues. The series begins with their chance meeting at an Overeaters Anonymous meeting, setting the stage for a heartfelt and comedic exploration of their journey as a couple. The show skillfully weaves together elements of romance, friendship, and family dynamics.

Viewers witness the challenges faced by the couple as they navigate societal expectations, weight loss efforts, and the humorous situations that arise in their day-to-day lives. The writing balances the humor derived from their weight-related struggles with genuine moments of emotional connection and growth.


“Mike & Molly” was produced by Chuck Lorre Productions and Warner Bros. Television. Mark Roberts, who also served as the creator, executive produced the series alongside Chuck Lorre, the prolific television producer known for other successful sitcoms like “Two and a Half Men” and “The Big Bang Theory.”

The show’s success can be attributed to the talented ensemble cast, sharp writing, and the ability to tackle sensitive topics with humor and sincerity. The chemistry between Gardell and McCarthy, in particular, contributed significantly to the show’s appeal.


“Mike & Molly” left a lasting impact on audiences by offering a fresh perspective on romance and relationships, breaking away from conventional norms. The series provided a platform for nuanced storytelling about characters who defied stereotypes, emphasizing that love and laughter are universal experiences.

The combination of a talented cast, well-crafted humor, and a genuine exploration of the complexities of relationships made “Mike and Molly Cast” a beloved sitcom during its six-season run. As it concluded in 2016, the show left behind a legacy of laughter, warmth, and a celebration of the human spirit in all its shapes and sizes.

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